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px215467
Wysłany: Wto 15:13, 15 Mar 2011
Temat postu: timberland scarpe Edgewise appliance in traumatic
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Edgewise appliance fixed in the trauma of anterior teeth
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, China [AbatedObjevUve: TOstudythelocMizafionof131 - integrininOralSubmucousFibrosis (OSF) andtherelationbe - tween ~ l-integrinandOSF. Method: SensitiveImmunohistochemiealandmorphometrieteehniguewereadoptedinexamina-tionoflocalizationandeontentof8l-integrininoralmucosaform3OpatientswithOSF (10forearly.moderateandadvancedstagerespectedly), 10normaloralmucosa. Result-Studyshowed: (1) Theoverexpressionof131-integrininmucosafromOSF, andtheimmunostainsfor131 a integrinwereprominentwithincytoplasm. andonthecellmembraneofspinocells, basio-cells, fibmblasts, vascularendothelialandsmoothmusclecells; (2) Therewasastatisticaldifferenceinexpressionof131-in-terinamongthreestages; (3) ThereWaslittleexpressionof131 a integrinimmunostainsinoralmocusa. Conclusion: 131 an inte-grineouldpiayaroleinthefibrogenieprocessofOSF. [Keywords] 131-integrin: oralsubmucousfibrosis (OSF); immunohistochemiey; morphometricanalysisB1 integrin as an important class of adhesion molecules, in many important physiological and pathological processes such as cell division, differentiation, apoptosis,
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, platelet aggregation, inflammation, tissue repair and invasion and metastasis of tumors plays an important role in [1.21. Recent studies show that some of Bl integrins and fibrotic diseases closely related to the development of guidelines. But B1 Integrins are involved in oral submucous fibrosis (oralsubmucousfibrosisOSF) pathogenesis,
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, is still rarely reported at home and abroad. In this study, immunohistochemistry and morphometric methods B1 integrin in OSF and normal oral mucosa of the expression level and distribution of p1 integrin in the pathogenesis of the role of OSF. Materials and Methods 1, material from the mouth of Xiangya School of Medicine Department of Pathology, 2000. -2004 Block of wax seal intact pathological diagnosis of OSF were screened early, middle and late cases of the 1O, general information shown in Table 1, normal control group mucosa (NOR) 10 例 from non-betel nut chewing habits, smoking, alcohol habits, healthy volunteers. Serial sections of the wax block, respectively, for HE and immunohistochemical staining, the former verification of pathology. Parts are drawn cheek. Table 1, samples of each group of the general information of r between the ages of each group comparison, p> 0.05 make teeth more stable, and can also form by adjusting the wires to adjust the front teeth occlusion, to avoid the trauma Yayun interference. [
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